![]() ![]() The above article has been published from a wire source with minimal modifications to the headline and text. ![]() The next step in the research will be to use molecular data from the study samples and integrate it with machine learning approaches to understand why some patients are cured of pneumonia, and others are not. "The application of machine learning and artificial intelligence to clinical data can be used to develop better ways to treat diseases like COVID-19 and to assist ICU physicians managing these patients," said Dr Catherine Gao, an instructor in pulmonary and critical care medicine at Feinberg and a Northwestern Medicine physician. They developed a new machine learning approach called CarpeDiem, which groups similar ICU patient days into clinical states based on electronic health record data. That's not what we saw," he said.įor the study, the team analysed 585 patients in the intensive care unit (ICU) at Northwestern Memorial Hospital with severe pneumonia and respiratory failure, 190 of whom had COVID-19. "If that were true and cytokine storms were underlying the long stay we see in patients with COVID-19, we would expect frequent transitions to states characterised by multi-organ failure. "The term 'cytokine storm' means an overwhelming inflammation that drives organ failure in your lungs, kidneys, brain and other organs," Singer explained. It is known that nitric oxide production by lightning leads to the formation of OH and other atmospheric oxidants, such as ozone and hydroperoxyl radicals (HO 2), through a variety of chemical reactions. The scientists also found evidence that COVID does not cause a "cytokine storm", so often believed to cause death. Hydroxyl radicals (OH) are the most important oxidizing species in the atmosphere and provide much of its ability to cleanse itself. The study was published in the Journal of Clinical Investigation. "Our data suggested that the mortality related to the virus itself is relatively low, but other things that happen during the ICU stay, like secondary bacterial pneumonia, offset that," Singer said. "Those who were cured of their secondary pneumonia were likely to live, while those whose pneumonia did not resolve were more likely to die. "Our study highlights the importance of preventing, looking for and aggressively treating secondary bacterial pneumonia in critically ill patients with severe pneumonia, including those with COVID-19," said senior author Dr Benjamin Singer, Associate Professor of Medicine at the university's Feinberg School of Medicine. Secondary bacterial infection of the lung (pneumonia) was widespread in patients with COVID, affecting almost half the patients who required support from mechanical ventilation. Interestingly, it may even exceed death rates from the viral infection, said researchers at Northwestern University. ![]() Homes and businesses were damaged in the Oklahoma towns of Noble, Newcastle and Tuttle, as well as Cole, where a tornado on April 19 killed three people.According to a study, secondary bacterial pneumonia that does not resolve was a key driver of death in patients with COVID. “All were weak or small … brief and shorter lived, most of them stayed out across our agricultural lands,” Husted said.Īs many as 10 tornadoes were reported in central Oklahoma, according to weather service meteorologist Scott Curl. Nearly 15 tornadoes were reported Thursday in northwestern Kansas, southwestern Nebraska and eastern Colorado, according to weather service meteorologist Ryan Husted in Goodland, Kansas.ĭamage was reported to the roof, windows and football stadium at the high school in the unincorporated community of Weskan in western Kansas, near the Colorado border, Husted said, but other twisters did little to no damage. Storms in parts of the southern Plains produced about two dozen small tornadoes but no reports of deaths or injuries, according to the National Weather Service, and more severe weather is possible Friday. ![]()
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